Complete Blood Count (CBC) Automated with Differential: CPT 85025


CPT Code:  85025 
Test Includes:  Hematocrit; hemoglobin; mean corpuscular volume (MCV); mean corpuscular hemoglobin (MCH); mean corpuscular hemoglobin concentration (MCHC); red cell distribution width (RDW); platelet count (RBC); red cell count; white blood cell count (WBC); Lymphocytes (LYM); Monocytes (MON); Granulocytes (GRA) 

Whole blood


Fill tube to capacity. 


Lavender-top (EDTA) tube. 


Invert tube 8 to 10 times immediately after tube is filled at the time of collection.

Reference Range:

Test Type Males Females
White Blood Cell (WBC) 4.0-10.5 103/µL 4.0-10.5 103/µL
Red Blood Cell (RBC) 4.6-6.2 106/µL 4.2-5.4 106/µL
Hemoglobin (HGB) 13.5-18 g/dL 12-16 g/dL
Hematocrit (HCT)  40-54% 38-47%
Mean Corpuscular Volume (MCV) 80-97 fL 80-97 fL
Mean Corpuscular Hemoglobin (MCH) 27-33 pg 27-33 pg
Mean Corpuscular Hemoglobin Concentration (MCHC) 31.5-35.7 g/dL 31.5-35.7 g/dL
Red Cell Distribution Width (RDW) 12.3-15.4% 12.3-15.4 %
Platelet Count (PLT) 150-450 103/µL 150-450 103/µL
Lymphocytes (LYM) 25-40% 25-40%
Monocytes (MON) 2-8% 2-8%
Granulocytes (GRA) 55-80% 55-80%


Temperature  Period                      
Refrigerated (2-8 ⁰C)  16 Days 


Use:    As a screening test to evaluate overall health; detect and/or identify a wide range of hematologic disorders; assist in managing medications/chemotherapeutic decisions. 
White Blood Cell (WBC): Blood contains a variety of white blood cells, the body’s defense system against infections. Elevated counts usually indicate infection or inflammation. A mild decrease in white blood cells is frequently seen in viral infections. Extremely elevated or decreased counts may indicate an active disease process, requiring medical evaluation by your physician. 
Red Blood Cell (RBC):  Red blood cells are the major component of blood. They are made in the bone marrow and released into the circulating blood. This count is a good indicator of the body’s ability to transport oxygenated blood to body tissues. A decreased number of red blood cells is associated with anemias, and other diseases affecting production of new red blood cells. 
Hemoglobin (HGB):  Approximately one-third of each red cell is comprised of hemoglobin, which contains iron. Hemoglobin carries oxygen from the lung to body tissues. Men tend to have higher hemoglobin levels than women. Low values may indicate anemia, blood loss, and other conditions associated with iron loss. 
Hematocrit (HCT):  The HCT is the comparison of the cellular portion of the blood to the serum (fluid) portion. This comparison is reported as a percentage. A low number of red blood cells causes a low HCT. Men tend to have higher hematocrits than women. The hematocrit is often used along with a hemoglobin to evaluate anemias.
MCV, MCH, and MCHC:  These calculations help your physician determine if significant abnormalities are present requiring additional testing. The MCV measures the actual size of the average red blood cell. The MCH represents the weight of hemoglobin in an average red blood cell. The MCHC uses the MCV and the MCH to compare the size of the red blood cell to the amount of hemoglobin present. These calculations are helpful in classifying anemias.
Red Cell Distribution Width (RDW):  The red cell distribution width or RDW is an analysis of the variation in size of all red blood cells tested. This evaluation is helpful in classifying anemias.
Platelet Count:  Platelets play a vital role in the blood clotting process. The platelets stop bleeding by sticking together and forming “plugs.” A variety of disease conditions can cause low numbers of platelets; these individuals tend to bleed more easily and excessively. Extremely low or high platelet counts may indicate blood disorders which require additional testing.
WBC Differential:  Five major types of white blood cells are normally found in the blood: neutrophils, lymphocytes, monocytes, eosinophils, and basophils. The “differential count” gives the percentage of each cell type. Increases or decreases in the cell percentages are consistent with certain medical conditions. These percentages assist your physician in determining a specific diagnosis or disease state.
Causes for Rejection:  Hemolysis; tube not filled with minimum fill volume; specimen drawn in any anticoagulant other than EDTA; specimens diluted or contaminated with IV fluid; clotted specimen; improper labeling; transfer tubes with whole blood; lavender-top (EDTA) tubes received with plasma removed.
Methodology:  Automated cell counter